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Figure 5 | Molecular Pain

Figure 5

From: Protein phosphatase 2A regulates central sensitization in the spinal cord of rats following intradermal injection of capsaicin

Figure 5

Effect of intrathecal infusion of the phosphatase inhibitors okadaic acid and fostriecin, or ACSF on decreased exploratory activity induced by capsaicin (0.1%, 50 μl) injection. Thirty min after capsaicin injection, okadaic acid (20 nM), fostriecin (30 nM), or ACSF was infused into the subarachnoid space of the spinal cord at the L5 segmental level of the rats. Compared to ACSF (n = 7), six parameters of spontaneous activity of the rats with okadaic acid (n = 7) and fostriecin (n = 5) infusion showed a significant decrease at every time interval. Each point represents the mean ± S.E.M. *p < 0.05.

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Molecular Pain

ISSN: 1744-8069

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