Fig. 4

Effects of escitalopram on the antinociceptive effect of morphine under the UCMS condition. The effects of escitalopram on the thermal pain sensitivity (a) and the antinociceptive effect of morphine (3 mg/kg; b) in a hot-plate test under the UCMS (white column vehicle, n = 11; gray column escitalopram 1 mg/kg, n = 12; black column escitalopram 3 mg/kg, n = 10) and non-stress (white column vehicle, n = 12; gray column escitalopram 1 mg/kg, n = 11; black column escitalopram 3 mg/kg, n = 9) conditions. Data are expressed as mean ± SEM.