Fig. 2
From: Mitochondrial and bioenergetic dysfunction in trauma-induced painful peripheral neuropathy
Partial sciatic nerve ligation causes persistently increased metabolic needs of injured nerves. a Total cellular oxygen consumption is persistently increased following nerve injury. This demonstrates that under ex vivo conditionsf b The oxygen consumption specific to mitochondrial respiration is also persistently increased following nerve injury. c Total extracellular acidification levels are persistently increased following nerve injury, demonstrating that injured nerves produce more acid than uninjured nerves. d Glycolysis specific extracellular acidification is also increased